Structure of PDB 6o11 Chain A

Receptor sequence
>6o11A (length=406) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
MIFSVDKVRADFPVLSREVNGLPLAYLDSAASAQKPSQVIDAEAEFYRHG
YAAVHRGIHTLSAQATEKMENVRKRASLFINARSAEELVFVRGTTEGINL
VANSWGNSNVRAGDNIIISQMEHHANIVPWQMLCARVGAELRVIPLNPDG
TLQLETLPTLFDEKTRLLAITHVSNVLGTENPLAEMITLAHQHGAKVLVD
GAQAVMHHPVDVQALDCDFYVFSGHKLYGPTGIGILYVKEALLQEMPPWE
GGGSMIATVSLSEGTTWTKAPWRFEAGTPNTGGIIGLGAALEYVSALGLN
NIAEYEQNLMHYALSQLESVPDLTLYGPQNRLGVIAFNLGKHHAYDVGSF
LDNYGIAVRTGHHAAMPLMAYYNVPAMCRASLAMYNTHEEVDRLVTGLQR
IHRLLG
3D structure
PDB6o11 Direct observation of intermediates in the SufS cysteine desulfurase reaction reveals functional roles of conserved active-site residues.
ChainA
Resolution1.84 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.8.1.7: cysteine desulfurase.
3.13.1.-
4.4.1.16: selenocysteine lyase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 C6P A A30 A31 T94 T95 H123 N175 D200 A202 Q203 S223 H225 K226 R359 R379 A30 A31 T94 T95 H123 N175 D200 A202 Q203 S223 H225 K226 R359 R379
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0005515 protein binding
GO:0008826 cysteine sulfinate desulfinase activity
GO:0009000 selenocysteine lyase activity
GO:0016740 transferase activity
GO:0016787 hydrolase activity
GO:0016829 lyase activity
GO:0030170 pyridoxal phosphate binding
GO:0031071 cysteine desulfurase activity
GO:0042803 protein homodimerization activity
Biological Process
GO:0001887 selenium compound metabolic process
GO:0006534 cysteine metabolic process
GO:0006790 sulfur compound metabolic process
GO:0016226 iron-sulfur cluster assembly
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:6o11, PDBe:6o11, PDBj:6o11
PDBsum6o11
PubMed31248989
UniProtP77444|SUFS_ECOLI Cysteine desulfurase (Gene Name=sufS)

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