Structure of PDB 6nsx Chain A

Receptor sequence
>6nsxA (length=94) Species: 9606 (Homo sapiens) [Search protein sequence]
MRHERVVIIKNMFHPMDFEDDPLVLNEIREDLRVECSKFGQIRKLLLFDR
HPDGVASVSFRDPEEADYCIQTLDGRWFGGRQITAQAWDGTTDY
3D structure
PDB6nsx Cus2 enforces the first ATP-dependent step of splicing by binding to yeast SF3b1 through a UHM-ULM interaction.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A D290 E294 R335 W336 F337 G338 G339 I342 D31 E35 R76 W77 F78 G79 G80 I83
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:6nsx, PDBe:6nsx, PDBj:6nsx
PDBsum6nsx
PubMed31110137
UniProtO43719|HTSF1_HUMAN 17S U2 SnRNP complex component HTATSF1 (Gene Name=HTATSF1)

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