Structure of PDB 6nsm Chain A

Receptor sequence
>6nsmA (length=194) Species: 208963 (Pseudomonas aeruginosa UCBPP-PA14) [Search protein sequence]
TRGRPRAFDRDTALQRAMDVFWVRGYEGASLAALTEAMEIRPPSLYAAFG
SKEGLFREALAHYLGQHGRYRRDVLDGAPSAREGVAELLRETVARFTSDE
FPRGSLVVLAALTGTPESEAVRDALSAERGESIRLFRERMRRGIADGDLA
ADTDMEELATFYATVLFGLSVQAKDRVPRERLLAVVERALRAWP
3D structure
PDB6nsm Structures of TetR family transcriptional regulator CifR_C99T-C181R Cysteines mutant complexed with 26bp double-strand operator DNA
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A R4 G5 R6 F10 R43 P45 S46 R2 G3 R4 F8 R41 P43 S44
BS02 dna A R4 G5 R6 P7 S32 L33 P44 Y48 S53 K54 R2 G3 R4 P5 S30 L31 P42 Y46 S51 K52
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0001217 DNA-binding transcription repressor activity
GO:0003677 DNA binding
Biological Process
GO:0009889 regulation of biosynthetic process
GO:0045892 negative regulation of DNA-templated transcription
GO:0080090 regulation of primary metabolic process
Cellular Component
GO:0032993 protein-DNA complex

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Cellular Component
External links
PDB RCSB:6nsm, PDBe:6nsm, PDBj:6nsm
PDBsum6nsm
PubMed
UniProtQ9HZR6

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