Structure of PDB 6nqa Chain A

Receptor sequence
>6nqaA (length=97) Species: 8355 (Xenopus laevis) [Search protein sequence]
PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSS
AVKALQEASEAYLVALFEDTNLCAIHAKRVTIKPKDIQLARRIRGER
3D structure
PDB6nqa Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L.
ChainA
Resolution3.54 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A Y41 R42 R72 R83 Q85 V117 Y4 R5 R35 R46 Q48 V80
BS02 dna A Y41 G44 V46 R63 L65 Y4 G7 V9 R26 L28
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:6nqa, PDBe:6nqa, PDBj:6nqa
PDBsum6nqa
PubMed30765112
UniProtP84233|H32_XENLA Histone H3.2

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