Structure of PDB 6nn6 Chain A

Receptor sequence
>6nn6A (length=97) Species: 8355 (Xenopus laevis) [Search protein sequence]
PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSS
AVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER
3D structure
PDB6nn6 Structural Basis for Recognition of Ubiquitylated Nucleosome by Dot1L Methyltransferase.
ChainA
Resolution3.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A H39 R40 Y41 R42 T45 R63 R72 F84 S86 T118 H2 R3 Y4 R5 T8 R26 R35 F47 S49 T81
BS02 dna A R40 P43 G44 V46 R49 K64 L65 P66 R83 R3 P6 G7 V9 R12 K27 L28 P29 R46
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:6nn6, PDBe:6nn6, PDBj:6nn6
PDBsum6nn6
PubMed30759380
UniProtP84233|H32_XENLA Histone H3.2

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