Structure of PDB 6nj9 Chain A

Receptor sequence
>6nj9A (length=99) Species: 8355 (Xenopus laevis) [Search protein sequence]
KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQS
SAVKALQEASEAYLVALFEDTNLCAIHAKRVTIKPKDIQLARRIRGERA
3D structure
PDB6nj9 Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L.
ChainA
Resolution2.96 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R40 Y41 G44 V46 R49 K64 L65 R4 Y5 G8 V10 R13 K28 L29
BS02 dna A R42 R72 R83 V117 T118 R6 R36 R47 V81 T82
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:6nj9, PDBe:6nj9, PDBj:6nj9
PDBsum6nj9
PubMed30765112
UniProtP84233|H32_XENLA Histone H3.2

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