Structure of PDB 6net Chain A

Receptor sequence
>6netA (length=427) Species: 441959 (Talaromyces stipitatus ATCC 10500) [Search protein sequence]
QPLSVGIVGGGIIGVILAAGLVRRGIDVKVFEQARGFREIGAGMAFTANA
VRCMEMLDPAIVWALRSSGHQAEARDYLRWVDGYHESSKRLYQLDAGIRG
FEACRRDQFLEALVKVLPEGIVECQKRLQKIHEKNETEKVTLEFADGTFA
HVDCVIGADGIRSRVRQHLFGEDSPYSHPHYSHKFAFRGLITMENAISAL
GEDKARTLNMHVGPNAHLIHYPVANETMVNIAAFVSDPEEWPLSLVGPAT
REEAMGYFANWNPGLRAVLGFMPENIDRWAMFDTYDYPAPFFSRGKICLV
GDAAHAAVPHHGAGACIGIEDALCATVLLAEVFVSTRGKSSIVRNRAIAA
AFGSFNAVRRVRAQWFVDSSRRVCDLYQQPEWADPQKRIKAENCFEEIKD
RSHKIWHFDYNSMLQEAIEKYRHNMGS
3D structure
PDB6net Structural basis for selectivity in flavin-dependent monooxygenase-catalyzed oxidative dearomatization.
ChainA
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.-.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 KJY A A55 D94 F119 A45 D76 F101 MOAD: Kd=21uM
BS02 FAD A V18 G19 G21 I23 F41 E42 Q43 M54 A55 R124 L146 D177 G178 R206 D322 G332 A333 G334 A335 C336 V8 G9 G11 I13 F31 E32 Q33 M44 A45 R106 L128 D159 G160 R188 D302 G312 A313 G314 A315 C316
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0071949 FAD binding
Biological Process
GO:0044550 secondary metabolite biosynthetic process
Cellular Component
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:6net, PDBe:6net, PDBj:6net
PDBsum6net
PubMed31346489
UniProtB8M9J8|TROPB_TALSN FAD-dependent monooxygenase tropB (Gene Name=tropB)

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