Structure of PDB 6neh Chain A

Receptor sequence
>6nehA (length=342) Species: 150095 (Thalictrum flavum subsp. glaucum) [Search protein sequence]
VNYLSGLGLSRLICLPMALRAAIELNVFEIIFQAGPEAQLSPAEIVAKIP
TKNPNAAIALDRILRMLGASSILSVTTMKDGRVYGLTEESRCLVADKNGV
SVVPMLLFTSDKAVVESFYNIKDVVLEEGVIPFDRTHGMDFFAYAGKEQS
VNKSFNQAMGAGSTIAFDEVFKVYKGFHDLKELVDVGGGIGTSLSNIISK
YPHIKGINFELPHVIADAPNYPGVEHIAGNMFEGVPNAQNILLKWVLHDW
DDERSIKILQNCWKALPEGGTVIVVEFVLPQILGNNAESFNALTPDLLMM
TLNPGGKERTTTEFDGLAKAAGFAETKFFPISQGLHVMEFHK
3D structure
PDB6neh Structural and functional characterization of the scoulerine 9-O methyltransferase from Thalictrum flavum.
ChainA
Resolution1.52 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.117: (S)-scoulerine 9-O-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH A F148 M165 S169 G193 E216 L217 N236 M237 K250 W251 F142 M159 S163 G187 E210 L211 N230 M231 K244 W245
BS02 SLX A M111 F147 F148 F161 M165 W251 H254 D255 F283 N297 P301 M305 N309 M105 F141 F142 F155 M159 W245 H248 D249 F277 N291 P295 M299 N303
BS03 SLX A L13 G14 S16 L7 G8 S10
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0008171 O-methyltransferase activity
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
GO:0030777 (S)-scoulerine 9-O-methyltransferase activity
GO:0046983 protein dimerization activity
Biological Process
GO:0032259 methylation

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Molecular Function
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Biological Process
External links
PDB RCSB:6neh, PDBe:6neh, PDBj:6neh
PDBsum6neh
PubMed
UniProtQ5C9L2

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