Structure of PDB 6n6j Chain A

Receptor sequence
>6n6jA (length=195) Species: 9606 (Homo sapiens) [Search protein sequence]
GESMAQRMVWVDLEMTGLDIEKDQIIEMACLITDSDLNILAEGPNLIIKQ
PDELLDSMSDWCKEHHGKSGLTKAVKESTITLQQAEYEFLSFVRQQTPPG
LCPLAGNSVHEDKKFLDKYMPQFMKHLHYRIIDVSTVKELCRRWYPEEYE
FAPKKAASHRALDDISESIKELQFYRNNIFKKKIDEKKRKIIENG
3D structure
PDB6n6j A dedicated diribonucleotidase resolves a key bottleneck for the terminal step of RNA degradation.
ChainA
Resolution1.317 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.15.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A E17 M18 G20 L21 W64 C65 H69 S111 E114 S138 H162 E14 M15 G17 L18 W61 C62 H66 S108 E111 S135 H159
BS02 rna A Y132 R133 Y129 R130
Gene Ontology
Molecular Function
GO:0000175 3'-5'-RNA exonuclease activity
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:6n6j, PDBe:6n6j, PDBj:6n6j
PDBsum6n6j
PubMed31225796
UniProtQ9Y3B8|ORN_HUMAN Oligoribonuclease, mitochondrial (Gene Name=REXO2)

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