Structure of PDB 6n22 Chain A

Receptor sequence
>6n22A (length=231) Species: 10090 (Mus musculus) [Search protein sequence]
WQYEDCKLARGGPPATIVAIDEESRNGTILVDNMLIKGTAGGPDPTIELS
LKDNVDYWVLLDPVKQMLFLNSTGRVLDRDPPMNIHSIVVQVQCVNKKVG
TVIYHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGA
TDIDDGPNGQIEYVIQYNPEDPTSNDTFEIPLMLTGNVVLRKRLNYEDKT
RYYVIIQANDRAQNLNERRTTTTTLTVDVLD
3D structure
PDB6n22 Structural determinants of protocadherin-15 mechanics and function in hearing and balance perception.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA A E27 E28 D83 D85 D121 E22 E23 D78 D80 D116
BS02 CA A E27 D85 D118 R119 D121 D159 E22 D80 D113 R114 D116 D154
BS03 CA A N120 N122 D157 D159 N163 D215 N115 N117 D152 D154 N158 D210
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007605 sensory perception of sound
GO:0048839 inner ear development
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0032420 stereocilium

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6n22, PDBe:6n22, PDBj:6n22
PDBsum6n22
PubMed32963095
UniProtQ99PJ1|PCD15_MOUSE Protocadherin-15 (Gene Name=Pcdh15)

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