Structure of PDB 6n10 Chain A

Receptor sequence
>6n10A (length=403) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
EEKWVVMVTAQTPTNIAVIKYWGKRDEVRILPINDSISVTLDPDHLCTLT
TVAVSPSFDRDRMWLNGKEISLSGSRYQNCLREIRSRADDVEDKEKGIKI
AKKDWEKLHLHIASHNNFPTAAGLASSAAGFACLVFALAKLMNVNEDPSQ
LSAIARQGSGSACRSLFGGFVKWNMGNKEDGSDSVAVQLVDDKHWDDLVI
IIAVVSSRQKETSSTSGMRESVETSLLLQHRAKEVVPVRILQMEEAIKNR
DFTSFTKLTCSDSNQFHAVCMDTSPPIFYMNDTSHRIISLVEKWNRSAGT
PEIAYTFDAGPNAVMIARNRKVAVELLQGLLYCFPPKPDTDMKSYVLGDT
SIVKEPQGIKDKIGSQDQKGEVSYFICSRPGRGPVVLQDQTQALLHPQTG
LPK
3D structure
PDB6n10 Substrate Specificity and Engineering of Mevalonate 5-Phosphate Decarboxylase.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.1.1.33: diphosphomevalonate decarboxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DP6 A A19 Y23 K26 R78 S161 G162 S163 R166 S216 T217 M220 A17 Y21 K24 R76 S159 G160 S161 R164 S214 T215 M218
Gene Ontology
Molecular Function
GO:0004163 diphosphomevalonate decarboxylase activity
GO:0005524 ATP binding
GO:0016829 lyase activity
GO:0016831 carboxy-lyase activity
GO:0042802 identical protein binding
Biological Process
GO:0008299 isoprenoid biosynthetic process
GO:0016126 sterol biosynthetic process
GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway
Cellular Component
GO:0005777 peroxisome
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6n10, PDBe:6n10, PDBj:6n10
PDBsum6n10
PubMed31268677
UniProtO23722|MVD1_ARATH Diphosphomevalonate decarboxylase MVD1, peroxisomal (Gene Name=MVD1)

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