Structure of PDB 6mzi Chain A

Receptor sequence
>6mziA (length=267) Species: 42789 (enterovirus D68) [Search protein sequence]
IESIIKTATDTVKSELGVVPSLNAVETGATSNTEPEEAIQTRTVINQHGV
SETLVENFLSRAALVSKRSFEYKDKNFFKWTINTRSFVQLRRKLELFTYL
RFDAEITILTTVAVGLPDLTLQAMFVPTGALTPEKQDSFHWQSGSNASVF
FKISDPPARITIPFMCINSAYSVFYDGFAGFEKNGLYGINPADTIGNLCV
RIVNEHQPVGFTVTVRVYMKPKHIKAWAPRPPRTLPYMSIANANYKGKER
APNALSAIIGNRDSVKT
3D structure
PDB6mzi Molecular basis for the acid-initiated uncoating of human enterovirus D68.
ChainA
Resolution3.46 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A E2 S3 I5 A33 T34 E60 N61 D116 T183 P185 K244 H245 P251 E2 S3 I5 A29 T30 E56 N57 D103 T161 P163 K222 H223 P229
External links