Structure of PDB 6mvu Chain A

Receptor sequence
>6mvuA (length=752) Species: 1225657 (Loktanella sp. 3ANDIMAR09) [Search protein sequence]
APESAKEAYAWLAEKGDFGHFIGGAWTAPGDLFATVNPATGQTLAQVSQA
TQADVDAAVKAARKAQPAWAKDGAARARVLYALARLLQKHARLFAVLETL
DNGKPIREARDIDVPLAQRHFYHHAGYAQLMGTEMPDRAPLGVCGQVIPW
NFPLLMLAWKIAPALAMGNTVVLKPAEWTPLTALLFADICGQAGVPAGVV
NIVTGDGAVGEMIVTAQVDKVAFTGSTAVGRRIREATAGTGKALSLELGG
KGPYVVCDDADIDSAVEGLVDAIWFNQGQVACAGSRLLVQEGIADVFHAK
LRARMDSLRIGDPLDKCIDIGAMVHPDQLARVRDMVAANTDGEVYQTAVP
AGCYYPPTLISGLAPASPLMQQEIFGPVLVSTTFRTPAEAVEIANNTAYG
LAASVWSENVNLALDLAPKLVAGIVWINGTNMMDAAAPFGGVRESGFGRE
GGWEGLAGYTRPAIATKSPAAVAAYTGDGAADGLDRTAKLYIGGKQTRPD
GGYSRAVYGPKGKLLGHASLSNRKDLRNAVEAMNAASGWSRTTGHLRAQI
LYFIGENLSARADEFANRIKDMTGKDGKAEVAASIDRLFSAAAWADKYDG
QVKGVPLRGVALAMKEPVGKIGILCPDAAPLLGLVSLMAPAIAMGNRVTL
AASEAFPLAATDFYQVLDTSDVPAGVVNILTGAHADLAEPMARHLDLDAV
WGLSGHAQVIEAASAGNLKRSWTGPFDPAHDHTRDILSHATEVKTIWVPY
GA
3D structure
PDB6mvu Crystal Structure of Aldehyde Dehydrogenase 16 Reveals Trans-Hierarchical Structural Similarity and a New Dimer.
ChainA
Resolution1.488 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) N165 E261 A295 E464
Catalytic site (residue number reindexed from 1) N151 E247 A281 E450
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 K4V A G221 G224 E225 V228 V243 R246 I247 A250 G207 G210 E211 V214 V229 R232 I233 A236 PDBbind-CN: -logKd/Ki=2.89,Ki=1290uM
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

View graph for
Molecular Function
External links
PDB RCSB:6mvu, PDBe:6mvu, PDBj:6mvu
PDBsum6mvu
PubMed30529746
UniProtA0A0Q3EUQ3

[Back to BioLiP]