Structure of PDB 6mut Chain A

Receptor sequence
>6mutA (length=747) Species: 342948 (Thermococcus onnurineus) [Search protein sequence]
MEIDELTALGGLLHDIGKPVQRAGLYSGDHSTQGARFLRDLAENTGRAEY
ELLSLFSEFHHKGHMKNDELMIRRIKELSPERFGLTMEDVLNALWIVYEA
DNLASGEREEGQPQASRPLYSVFNPGKAYPWAELDFEKELPVPGDVFSIR
SQDYRELVKRLWEELSKAKLRSDRLLPVLEKYLTFVSSVTSEGNIISLYD
HMRMTSAIALAMLRAGCTAEDVRSGRCRKEKRFLLIEGDFSGIQDFIYRV
SGKGTLKYLRARSAYLELIGWDVVLEILSRLGLTRANVVFNAGGHFMIIA
QNTPDAVKELEEIRAKAVEWLYREFESDLYLAIEWEPVSGREFGREGGKN
LFAEARKRLKHKLTVRKLKRFGEIKGLFEHGHTERLAECPVCGRELPEGK
LEPSASDPETKVCPTCNRLVSLGGNLPKLLGFGRTAKNDAGVLVEGPFSG
FVPYLQGGRPVGEQILVKNTLNPGEIPESAQFVPYFVADYFKKDPKGGVA
TFEELSMASTGTRRLGVMKGDVDRLGEFFSSMDSPSKLATASRFMDYFFK
GYIGAIIEGKFGYIIGDVPSLRDWPEEPDIVVVYAGGDDFFIVGAWDQIF
ELAFRVRRAFNAYTGGKLTLSVGLGYFDERTPIYRMADVVSERLDTAKDE
GRNRVFVVPLDGKHKLSYEWNHYEELWRTYAPRIYLESKKGLLWKLLEIR
ELYVRVRWAYLTAYLLGRHGLSDLFPELVQPVYWVDGVLKIVLMAVR
3D structure
PDB6mut Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity.
ChainA
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A R385 R630 R385 R630
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016740 transferase activity
GO:0042802 identical protein binding
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:6mut, PDBe:6mut, PDBj:6mut
PDBsum6mut
PubMed30503773
UniProtB6YWB8|CAS10_THEON CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A) (Gene Name=csm1)

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