Structure of PDB 6mpx Chain A

Receptor sequence
>6mpxA (length=673) Species: 9606 (Homo sapiens) [Search protein sequence]
HGFLVTRHSQTIDDPQCPSGTKILYHGYSLLYVQGNERAHGQDLGTAGSC
LRKFSTMPFLFCNINNVCNFASRNDYSYWLSTPEPMPMSMAPITGENIRP
FISRCAVCEAPAMVMAVHSQTIQIPPCPSGWSSLWIGYSFVMHTSAGAEG
SGQALASPGSCLEEFRSAPFIECHGRGTCNYYANAYSFWLATIERSEMFK
KPTPSTLKAGELRTHVSRCQVCMGTGYLLVKHSQTDQEPMCPVGMNKLWS
GYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDK
SYWLSTTAPLPMMPVAEDEIKPYISRCSVCEAPAIAIAVHSQDVSIPHCP
AGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRG
TCHYYANKYSFWLTTIPEQSFQGSPSADTLKAGLIRTHISRCQVCMAPGF
LVTRHSQTIDDPQCPSGTKILYHGYSLLYVQGNERAHGQDLGTAGSCLRK
FSTMPFLFCNINNVCNFASRNDYSYWLSTPEPMPMSMAPITGENIRPFIS
RCAVCEAPAMVMAVHSQTIQIPPCPSGWSSLWIGYSFVMHTSAGAEGSGQ
ALASPGSCLEEFRSAPFIECHGRGTCNYYANAYSFWLATIERSEMFKKPT
PSTLKAGELRTHVSRCQVCMRRT
3D structure
PDB6mpx A chloride ring is an ancient evolutionary innovation mediating the assembly of the collagen IV scaffold of basement membranes.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CL A A521 R523 A518 R520
BS02 CL A Y412 N513 Y409 N510
BS03 CL A Y189 Y288 Y186 Y285
BS04 CL A A74 R76 A71 R73
BS05 CL A A298 R300 A295 R297
Gene Ontology
Molecular Function
GO:0005201 extracellular matrix structural constituent
Cellular Component
GO:0005581 collagen trimer

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Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:6mpx, PDBe:6mpx, PDBj:6mpx
PDBsum6mpx
PubMed30923125
UniProtP02462;
P08572

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