Structure of PDB 6mlq Chain A

Receptor sequence
>6mlqA (length=411) Species: 9823 (Sus scrofa) [Search protein sequence]
RECISIHVGQAGVQIGNACWELYCLEHGIQPDHVPRAVFVDLEPTVIDEV
RTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQ
CTGLQGFSVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVS
TAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLN
RLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRAHFPLATYAPVISA
EKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDV
NAAIATIKTKRTIQFVDWCPTGFKVGINYEPPTVVPGGDLAKVQRAVCML
SNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAAL
EKDYEEVGVDS
3D structure
PDB6mlq Interplay between the Kinesin and Tubulin Mechanochemical Cycles Underlies Microtubule Tip Tracking by the Non-motile Ciliary Kinesin Kif7.
ChainA
Resolution4.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A G10 Q11 G9 Q10
BS02 GTP A Q11 A12 N101 G142 G143 T145 G146 I171 Y224 N228 Q10 A11 N73 G114 G115 T117 G118 I143 Y196 N200
Gene Ontology
Molecular Function
GO:0005200 structural constituent of cytoskeleton
GO:0005525 GTP binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0000278 mitotic cell cycle
GO:0007017 microtubule-based process
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005874 microtubule
GO:0031514 motile cilium

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Cellular Component
External links
PDB RCSB:6mlq, PDBe:6mlq, PDBj:6mlq
PDBsum6mlq
PubMed31031197
UniProtP02550|TBA1A_PIG Tubulin alpha-1A chain (Gene Name=TUBA1A)

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