Structure of PDB 6ml6 Chain A

Receptor sequence

>6ml6A (length=143) Species: 10090 (Mus musculus) [Search protein sequence]

GSKSFTCDQCGKYFSQKRQLKSHYRVHTGHSLPECSHCHRKFMDVSQLKK
HLRTHTGEKPFTCEICGKSFTAKSSLQTHIRIHRGEKPYSCSICGKCFSD
SSAKRRHCILHTGKKPFSCPECGLQFARLDNLKAHLKIHSKEK

3D structure

PDB

6ml6 Structural basis of specific DNA binding by the transcription factor ZBTB24.

Chain

Resolution

1.54 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	A	Q419 K422 H423 T426 K431 F442 T443 S447 H451 I454 K468 F470 D472 R478 H479 L482 L496 R500 N503 H507 I510	Q47 K50 H51 T54 K59 F70 T71 S75 H79 I82 K96 F98 D100 R106 H107 L110 L124 R128 N131 H135 I138
BS02	dna	A	Q391 D416 V417 S418 Q419 K421 K422 S474 R477 D502 K505	Q19 D44 V45 S46 Q47 K49 K50 S102 R105 D130 K133
BS03	ZN	A	C379 C382 H395 H399	C7 C10 H23 H27
BS04	ZN	A	C407 C410 H423 H427	C35 C38 H51 H55
BS05	ZN	A	C435 C438 H451 H455	C63 C66 H79 H83
BS06	ZN	A	C463 C466 H479 H483	C91 C94 H107 H111
BS07	ZN	A	C491 C494 H507 H511	C119 C122 H135 H139

External links

PDB	RCSB:6ml6, PDBe:6ml6, PDBj:6ml6
PDBsum	6ml6
PubMed	31226215
UniProt	Q80X44\|ZBT24_MOUSE Zinc finger and BTB domain-containing protein 24 (Gene Name=Zbtb24)