Structure of PDB 6ml2 Chain A

Receptor sequence

>6ml2A (length=139) Species: 10090 (Mus musculus) [Search protein sequence]

SKSFTCDQCGKYFSQKRQLKSHYRVHTSLPECSHCHRKFMDVSQLKKHLR
THTGEKPFTCEICGKSFTAKSSLQTHIRIHRGEKPYSCSICGKCFSDSSA
KRRHCILHTGKKPFSCPECGLQFARLDNLKAHLKIHSKE

3D structure

PDB

6ml2 Structural basis of specific DNA binding by the transcription factor ZBTB24.

Chain

Resolution

1.874 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	A	M415 Q419 K422 H423 K431 F442 T443 H451 I454 F470 D472 R478 H479 L482 R500 N503	M40 Q44 K47 H48 K56 F67 T68 H76 I79 F95 D97 R103 H104 L107 R125 N128
BS02	dna	A	K445 S474 R477	K70 S99 R102
BS03	ZN	A	C379 C382 H395 H399	C6 C9 H22 H26
BS04	ZN	A	C407 C410 H423 H427	C32 C35 H48 H52
BS05	ZN	A	C435 C438 H451 H455	C60 C63 H76 H80
BS06	ZN	A	C463 C466 H479 H483	C88 C91 H104 H108
BS07	ZN	A	C491 C494 H507 H511	C116 C119 H132 H136

External links

PDB	RCSB:6ml2, PDBe:6ml2, PDBj:6ml2
PDBsum	6ml2
PubMed	31226215
UniProt	Q80X44\|ZBT24_MOUSE Zinc finger and BTB domain-containing protein 24 (Gene Name=Zbtb24)