Structure of PDB 6mj7 Chain A
Receptor sequence
>6mj7A (length=54) Species:
9606
(Homo sapiens) [
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GSNMVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVCEGKGLHRGHTKLA
FPSP
3D structure
PDB
6mj7
ZZ-dependent regulation of p62/SQSTM1 in autophagy.
Chain
A
Resolution
1.412 Å
3D
structure
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Enzymatic activity
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
ZN
A
C128 C131 C151 C154
C11 C14 C34 C37
BS02
ZN
A
C142 C145 H160 H163
C25 C28 H43 H46
BS03
ARG
A
V126 I127 D129 N132 D147 D149
V9 I10 D12 N15 D30 D32
PDBbind-CN
: -logKd/Ki=2.82,Kd=1.5mM
Gene Ontology
Molecular Function
GO:0008270
zinc ion binding
View graph for
Molecular Function
External links
PDB
RCSB:6mj7
,
PDBe:6mj7
,
PDBj:6mj7
PDBsum
6mj7
PubMed
30349045
UniProt
Q13501
|SQSTM_HUMAN Sequestosome-1 (Gene Name=SQSTM1)
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