Structure of PDB 6mfe Chain A

Receptor sequence
>6mfeA (length=259) Species: 6183 (Schistosoma mansoni) [Search protein sequence]
GAMIESSTTIQVISAGLPRTGTKSLKNALEIIYHKPCYHMFEIIFNKQSD
IIKWQNLIHDSHMITTPPPLTTKTIAIYDKLKELLDGYIATTDLPTCGFY
KDLMNIYPNAKVLLTIRDKYDWLHSLRKVVLPKSNDPWKLKIEEGDKVLG
LNSDFYKLTEDSLKFAFQKDDLNFDDDQVLLECYDEYNRLVQETVPSDRL
LVLRLGDGWEPLCKFLNVEIPNGIDYPCVNSHHQMTQLTEQLIKYKSLDA
IIHMFPDLI
3D structure
PDB6mfe Design, Synthesis, and Characterization of Novel Small Molecules as Broad Range Antischistosomal Agents.
ChainA
Resolution1.444 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A3P A R17 T18 G19 T20 K21 S22 R115 S123 L203 X226 N228 S229 H230 R19 T20 G21 T22 K23 S24 R117 S125 L205 X228 N230 S231 H232
BS02 S73 A M38 I42 F43 D91 V127 V128 I140 D144 L147 F153 T157 M233 L236 M40 I44 F45 D93 V129 V130 I142 D146 L149 F155 T159 M235 L238
Gene Ontology
Molecular Function
GO:0016740 transferase activity

View graph for
Molecular Function
External links
PDB RCSB:6mfe, PDBe:6mfe, PDBj:6mfe
PDBsum6mfe
PubMed30344901
UniProtG4VLE5

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