Structure of PDB 6mf6 Chain A

Receptor sequence
>6mf6A (length=244) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
AQQAVLRKELIATSTNVIKSEISLRILASECHLTLNGIVEAEAQYKMGGL
PKSRLPKIKHPMIVTKWVDYSNKHGFSYQLSTEDIGVLFNNGTTVLRLAD
AEEFWYISYDDREGWVASHYLLSEKPRELSRHLEVVDFFAKYMKANLHKD
DVFLRRYTRYKPFVMFELSDGTFQFNFKDHHKMAISDGGKLVTYISPSHE
STTYPLVEVLKYGEIPGYPESNFREKLTLIKEGLKQKSTIVTVD
3D structure
PDB6mf6 Distinct surfaces on Cdc5/PLK Polo-box domain orchestrate combinatorial substrate recognition during cell division.
ChainA
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.21: polo kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A W555 W565 V566 D611 D612 F614 R616 S630 W105 W115 V116 D150 D151 F153 R155 S169
External links
PDB RCSB:6mf6, PDBe:6mf6, PDBj:6mf6
PDBsum6mf6
PubMed32099015
UniProtP32562|CDC5_YEAST Cell cycle serine/threonine-protein kinase CDC5/MSD2 (Gene Name=CDC5)

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