Structure of PDB 6mf5 Chain A

Receptor sequence
>6mf5A (length=250) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
AQRRLNDLAREARIRRAQQAVLRKELIATSTNVIKSEISLRILASECHLT
LNGIVEAEAQYKIKHPMIVTKWVDYSNKHGFSYQLSTEDIGVLFNNGTTV
LRLAEEFWYISYDDREGWVASHYLLSEKPRELSRHLEVVDFFAKYMKANL
SRVSTKDDVFLRRYTRYKPFVMFELSDGTFQFNFKDHHKMAISDGGKLVT
YISPSHESTTYPLVEVLKYGEIPGYPESNFREKLTLIKEGLKQKSTIVTV
3D structure
PDB6mf5 Distinct surfaces on Cdc5/PLK Polo-box domain orchestrate combinatorial substrate recognition during cell division.
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.21: polo kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A K516 W517 D519 Y520 Y592 N596 L597 S598 R620 H641 K643 K71 W72 D74 Y75 Y145 N149 L150 S151 R166 H187 K189
External links
PDB RCSB:6mf5, PDBe:6mf5, PDBj:6mf5
PDBsum6mf5
PubMed32099015
UniProtP32562|CDC5_YEAST Cell cycle serine/threonine-protein kinase CDC5/MSD2 (Gene Name=CDC5)

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