Structure of PDB 6men Chain A

Receptor sequence
>6menA (length=162) Species: 694007 (Tylonycteris bat coronavirus HKU4) [Search protein sequence]
SKYKHTVINNSVTLVLGDAIQIASLLPKCILVNAANRHLKHGGGIAGVIN
KASGGDVQEESDEYISNNGPLHVGDSVLLKGHGLADAILHVVGPDARNNE
DAALLKRCYKAFNKHTIVVTPLISAGIFSVDPKVSFEYLLANVTTTTYVV
VNNEDIYNTLAT
3D structure
PDB6men ADP-Ribose and Analogues bound to the DeMARylating Macrodomain from the Bat Coronavirus HKU4
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.56: mRNA (guanine-N(7))-methyltransferase.
2.1.1.57: methyltransferase cap1.
2.7.7.48: RNA-directed RNA polymerase.
2.7.7.50: mRNA guanylyltransferase.
3.1.13.-
3.4.19.12: ubiquitinyl hydrolase 1.
3.4.22.-
3.6.4.12: DNA helicase.
3.6.4.13: RNA helicase.
4.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADQ A D325 A326 A341 N343 K347 H348 G350 I352 P428 S431 G433 I434 F435 V457 D18 A19 A34 N36 K40 H41 G43 I45 P121 S124 G126 I127 F128 V150
External links
PDB RCSB:6men, PDBe:6men, PDBj:6men
PDBsum6men
PubMed
UniProtP0C6W3|R1AB_BCHK4 Replicase polyprotein 1ab (Gene Name=rep)

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