Structure of PDB 6mea Chain A

Receptor sequence
>6meaA (length=162) Species: 694007 (Tylonycteris bat coronavirus HKU4) [Search protein sequence]
SKYKHTVINNSVTLVLGDAIQIASLLPKCILVNAANRHLKHGGGIAGVIN
KASGGDVQEESDEYISNNGPLHVGDSVLLKGHGLADAILHVVGPDARNNE
DAALLKRCYKAFNKHTIVVTPLISAGIFSVDPKVSFEYLLANVTTTTYVV
VNNEDIYNTLAT
3D structure
PDB6mea ADP-Ribose and Analogues bound to the DeMARylating Macrodomain from the Bat Coronavirus HKU4
ChainA
Resolution1.35 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.1.1.56: mRNA (guanine-N(7))-methyltransferase.
2.1.1.57: methyltransferase cap1.
2.7.7.48: RNA-directed RNA polymerase.
2.7.7.50: mRNA guanylyltransferase.
3.1.13.-
3.4.19.12: ubiquitinyl hydrolase 1.
3.4.22.-
3.6.4.12: DNA helicase.
3.6.4.13: RNA helicase.
4.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 APR A D325 A326 A341 N343 G349 G351 I352 L429 S431 A432 G433 I434 F435 V457 N459 D18 A19 A34 N36 G42 G44 I45 L122 S124 A125 G126 I127 F128 V150 N152
External links
PDB RCSB:6mea, PDBe:6mea, PDBj:6mea
PDBsum6mea
PubMed
UniProtP0C6W3|R1AB_BCHK4 Replicase polyprotein 1ab (Gene Name=rep)

[Back to BioLiP]