Structure of PDB 6mb7 Chain A

Receptor sequence
>6mb7A (length=265) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
SFATRTSLAADLAALGLAWGDAIMVHAAVSRVGRLLDGPDTIIAALRDTV
GPGGTVLAYADWEARYEDLVDDAGRVPPEWREHVPPFDPQRSRAIRDNGV
LPEFLRTTPGTLRSGNPGASLVALGAKAEWFTADHPLDYGYGEGSPLAKL
VEAGGKVLMLGAPLDTLTLLHHAEHLADIPGKRIKRIEVPFATPTGTQWR
MIEEFDTGDPIVAGLAEDYFAGIVTEFLASGQGRQGLIGAAPSVLVDAAA
ITAFGVTWLEKRFGT
3D structure
PDB6mb7 Encoding of Promiscuity in an Aminoglycoside Acetyltransferase.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.81: aminoglycoside N(3)-acetyltransferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 PAR A Y65 H177 T213 G214 D215 E223 Y59 H171 T207 G208 D209 E217
Gene Ontology
Molecular Function
GO:0008080 N-acetyltransferase activity
GO:0016746 acyltransferase activity
GO:0046353 aminoglycoside 3-N-acetyltransferase activity
Biological Process
GO:0046677 response to antibiotic

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Molecular Function

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Biological Process
External links
PDB RCSB:6mb7, PDBe:6mb7, PDBj:6mb7
PDBsum6mb7
PubMed30347146
UniProtQ51405

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