Structure of PDB 6mb6 Chain A

Receptor sequence
>6mb6A (length=268) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
SFATRTSLAADLAALGLAWGDAIMVHAAVSRVGRLLDGPDTIIAALRDTV
GPGGTVLAYADWEARYEDLVDDAGRVPPEWREHVPPFDPQRSRAIRDNGV
LPEFLRTTPGTLRSGNPGASLVALGAKAEWFTADHPLDYGYGEGSPLAKL
VEAGGKVLMLGAPLDTLTLLHHAEHLADIPGKRIKRIEVPFATPTGTQWR
MIEEFDTGDPIVAGLAEDYFAGIVTEFLASGQGRQGLIGAAPSVLVDAAA
ITAFGVTWLEKRFGTPSP
3D structure
PDB6mb6 Encoding of Promiscuity in an Aminoglycoside Acetyltransferase.
ChainA
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.81: aminoglycoside N(3)-acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COA A A33 A34 V35 S36 N104 G105 V106 F110 A168 P169 T172 A27 A28 V29 S30 N98 G99 V100 F104 A162 P163 T166
BS02 COA A R71 R102 R65 R96
Gene Ontology
Molecular Function
GO:0008080 N-acetyltransferase activity
GO:0016746 acyltransferase activity
GO:0046353 aminoglycoside 3-N-acetyltransferase activity
Biological Process
GO:0046677 response to antibiotic

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Molecular Function
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Biological Process
External links
PDB RCSB:6mb6, PDBe:6mb6, PDBj:6mb6
PDBsum6mb6
PubMed30347146
UniProtQ51405

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