Structure of PDB 6m79 Chain A
Receptor sequence
>6m79A (length=460) Species:
3702
(Arabidopsis thaliana) [
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KKTIVWFRRDLRIEDNPALAAAAHEGSVFPVFIWCPEEEGQFYPGRASRW
WMKQSLAHLSQSLKALGSDLTLIQTHNTISAILDCIRVTGPTKVVFNHLY
DPVSLVRDHTVKEKLVERGISVQSYNGDLLYEPWEIYCEKGKPFTSFNSY
WKKCLDMSIESVMLPPPWRLMPIIWACSIEELGLENEAEKPSNALLTRAW
SPGWSNADKLLNEFIEKQLIDYAKNSKKVVGNSTSLLSPYLHFGEISVRH
VFQCARMKQIIWARDKNSEGEESADLFLRGIGLREYSRYICFNFPPWDAD
VDKFKAWRQGRTGYPLVDAGMRELWATGWMHNRIRVIVSSFGVKFLLLPW
KWGMKYFWDTLLDADLECDILGWQYISGSIPDGHELDRLDNPALQGAKYD
PEGEYIRQWLPELARLPTEWIHHPWDAPLTVLKASGVELGTNYAKPIVDI
DTARELLAKA
3D structure
PDB
6m79
Structural insights into the photoactivation of Arabidopsis CRY2.
Chain
A
Resolution
3.1 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB)
G290 L293 W321 N356 W374 W397
Catalytic site (residue number reindexed from 1)
G280 L283 W297 N332 W350 W373
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
AMP
A
N356 Y399 D406
N332 Y375 D382
BS02
FAD
A
Y232 T244 S245 L246 G290 N356 R359 C392
Y222 T234 S235 L236 G280 N332 R335 C368
Gene Ontology
Molecular Function
GO:0005515
protein binding
GO:0005524
ATP binding
GO:0009881
photoreceptor activity
GO:0009882
blue light photoreceptor activity
GO:0016301
kinase activity
GO:0042802
identical protein binding
GO:0042803
protein homodimerization activity
GO:0046872
metal ion binding
GO:0071949
FAD binding
GO:0097159
organic cyclic compound binding
Biological Process
GO:0006139
nucleobase-containing compound metabolic process
GO:0006325
chromatin organization
GO:0006338
chromatin remodeling
GO:0006950
response to stress
GO:0006952
defense response
GO:0007623
circadian rhythm
GO:0009414
response to water deprivation
GO:0009416
response to light stimulus
GO:0009637
response to blue light
GO:0009638
phototropism
GO:0009646
response to absence of light
GO:0009785
blue light signaling pathway
GO:0009909
regulation of flower development
GO:0009911
positive regulation of flower development
GO:0010075
regulation of meristem growth
GO:0010118
stomatal movement
GO:0010244
response to low fluence blue light stimulus by blue low-fluence system
GO:0010617
circadian regulation of calcium ion oscillation
GO:0042752
regulation of circadian rhythm
GO:0046777
protein autophosphorylation
GO:0048574
long-day photoperiodism, flowering
GO:0051607
defense response to virus
GO:0072387
flavin adenine dinucleotide metabolic process
GO:1901371
regulation of leaf morphogenesis
GO:1902347
response to strigolactone
GO:2000028
regulation of photoperiodism, flowering
GO:2000379
positive regulation of reactive oxygen species metabolic process
Cellular Component
GO:0000325
plant-type vacuole
GO:0005634
nucleus
GO:0005737
cytoplasm
GO:0016604
nuclear body
GO:0016605
PML body
View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB
RCSB:6m79
,
PDBe:6m79
,
PDBj:6m79
PDBsum
6m79
PubMed
33199893
UniProt
Q96524
|CRY2_ARATH Cryptochrome-2 (Gene Name=CRY2)
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