Structure of PDB 6m63 Chain A

Receptor sequence
>6m63A (length=359) Species: 6100,266835 [Search protein sequence]
GDFVRNWQLVAAVPLFQKLGPAVLVEIVRALRARTVPAGAVICRIGEPGD
RMFFVVEGSVSVATNWGNVYITADKQKNGIKANFKIRHNVEGGGVQLAYH
YQQNTPIGDGPVLLPDNHYLSVQSKLSKDPNEKRDHMVLLEFVTAAGITL
DEYSKGEELFTGVVPILVELDGDVNGHKFSVRGEGEGDATNGKLTLKFIC
TTGKLPVPWPTLVTTLVQCFARYPDHMKQHDFFKSAMPEGYIQERTIVFK
DDGTYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNRVNPVEL
GPGAFFGEMALISGEPRVATVSAATTVSLLSLHSADFQMLCSSSPEIAEI
FRKTALERR
3D structure
PDB6m63 A high-performance genetically encoded fluorescent indicator for in vivo cAMP imaging.
ChainA
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CMP A V71 F330 G331 E332 M333 A334 R341 V342 A343 R382 V62 F306 G307 E308 M309 A310 R317 V318 A319 R358
Gene Ontology
Molecular Function
GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity
Biological Process
GO:0006091 generation of precursor metabolites and energy
GO:0008218 bioluminescence

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Molecular Function
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Biological Process
External links
PDB RCSB:6m63, PDBe:6m63, PDBj:6m63
PDBsum6m63
PubMed36097007
UniProtP42212|GFP_AEQVI Green fluorescent protein (Gene Name=GFP);
Q98GN8|CNGK1_RHILO Cyclic nucleotide-gated potassium channel mll3241 (Gene Name=mll3241)

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