Structure of PDB 6m4x Chain A

Receptor sequence
>6m4xA (length=207) Species: 6500 (Aplysia californica) [Search protein sequence]
SQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKVDSSTNEVD
LVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQV
LSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGVTCAVKFGSWVYSG
FEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLV
VKFRERR
3D structure
PDB6m4x The crystal structure of Ac-AChBP in complex with LvIA analogs reveals the mechanism of its selectivity towards different nAChR subtypes
ChainA
Resolution2.998 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A W145 Y186 C188 C189 E191 Y193 W146 Y187 C189 C190 E192 Y194
BS02 peptide A Y53 R77 V106 M114 I116 D162 S165 Y54 R78 V107 M115 I117 D163 S166
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0005216 monoatomic ion channel activity
GO:0005230 extracellular ligand-gated monoatomic ion channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0034220 monoatomic ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function

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Cellular Component
External links
PDB RCSB:6m4x, PDBe:6m4x, PDBj:6m4x
PDBsum6m4x
PubMed
UniProtQ8WSF8

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