Structure of PDB 6m38 Chain A

Receptor sequence
>6m38A (length=534) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
DERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLA
VGGIPLFYMELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVGFYY
NVIIAWSLRFFFASFTNSLPWTSCNNIWNTPNCRPFEGHVEGFQSAASEY
FNRYILELNRSEGIHDLGAIKWDMALCLLIVYLICYFSLWKGISTSGKVV
WFTALFPYAVLLILLIRGLTLPGSFLGIQYYLTPNFSAIYKAEVWVDAAT
QVFFSLGPGFGVLLAYASYNKYHNNVYKDALLTSFINSATSFIAGFVIFS
VLGYMAHTLGVRIEDVATEGPGLVFVVYPAAIATMPASTFWALIFFMMLA
TLGLDSSFGGMEAIITALSDEFPKIKRNRELFVAGLFSLYFVVGLASCTQ
GGFYFFHLLDRYAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPP
GRYWQVCWRFVAPIFLLFITVYGLIGYEPLTYADYVYPSWANALGWCIAG
SSVVMIPAVAIFKLLSTPGSLRQRFTILTTPWRD
3D structure
PDB6m38 Structural basis of norepinephrine recognition and transport inhibition in neurotransmitter transporters.
ChainA
Resolution3.001 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 29E A F43 A44 D46 A117 V120 Y124 F319 S320 F325 G425 F19 A20 D22 A93 V96 Y100 F254 S255 F260 G360
BS02 DMU A R133 F136 A137 D238 L241 R109 F112 A113 D173 L176
BS03 CLR A Y273 L277 I351 Y208 L212 I286
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:6m38, PDBe:6m38, PDBj:6m38
PDBsum6m38
PubMed33850134
UniProtQ7K4Y6|DAT_DROME Sodium-dependent dopamine transporter (Gene Name=DAT)

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