Structure of PDB 6m2r Chain A

Receptor sequence
>6m2rA (length=536) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
DERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLA
VGGIPLFYMELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYY
NVIIAWSLRFFFASFTNSLPWTSCNNIWNTPNCRPFEGHVEGFQSAASEY
FNRYILELNRSEGIHDLGAIKWDMALCLLIVYLICYFSLWKGISTSGKVV
WFTALFPYAVLLILLIRGLTLPGSFLGIQYYLTPNFSAIYKAEVWVDAAT
QVFFSLGPGFGVLLAYASYNKYHNNVYKDALLTSFINSATSFIAGFVIFS
VLGYMAHTLGVRIEDVATEGPGLVFVVYPAAIATMPASTFWALIFFMMLA
TLGLDSSFGGSEAIITALSDEFPKIKRNRELFVAGLFSLYFVVGLASCTQ
GGFYFLHLLDRYAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPP
GRYWQVCWRFVAPIFLLFITVYGLIGYEPLTYADYVYPSWANALGWCIAG
SSVVMIPAVAIFKLLSTPGSLRQRFTILTTPWRDQQ
3D structure
PDB6m2r Structural basis of norepinephrine recognition and transport inhibition in neurotransmitter transporters.
ChainA
Resolution2.802 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DMU A R133 F136 P144 Y219 L241 R109 F112 P120 Y154 L176
BS02 Y01 A F357 G516 Y518 F292 G451 Y453
BS03 CLR A I41 Y273 L277 I351 I17 Y208 L212 I286
BS04 LNR A V120 F325 V96 F260
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:6m2r, PDBe:6m2r, PDBj:6m2r
PDBsum6m2r
PubMed33850134
UniProtQ7K4Y6|DAT_DROME Sodium-dependent dopamine transporter (Gene Name=DAT)

[Back to BioLiP]