Structure of PDB 6m2h Chain A

Receptor sequence
>6m2hA (length=119) Species: 243232 (Methanocaldococcus jannaschii DSM 2661) [Search protein sequence]
MEALVLVGHGSRLPYSKELLVKLAEKVKERNLFPIVEIGLMEFSEPTIPQ
AVKKAIEQGAKRIIVVPVFLAHGIHTTRDIPRLLGLIEEIPEDVEIIYRE
PIGADDRIVDIIIDRAFGR
3D structure
PDB6m2h The nickel-sirohydrochlorin formation mechanism of the ancestral class II chelatase CfbA in coenzyme F430 biosynthesis.
ChainA
Resolution3.1 Å
3D
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Enzymatic activity
Enzyme Commision number 4.99.1.11: sirohydrochlorin nickelchelatase.
4.99.1.3: sirohydrochlorin cobaltochelatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NI A H9 H75 H9 H75
BS02 SHN A H9 S11 R12 F43 L70 G73 I74 H75 H9 S11 R12 F43 L70 G73 I74 H75
Gene Ontology
Molecular Function
GO:0016151 nickel cation binding
GO:0016829 lyase activity
GO:0016852 sirohydrochlorin cobaltochelatase activity
GO:0046872 metal ion binding
GO:0050897 cobalt ion binding
Biological Process
GO:0009236 cobalamin biosynthetic process
GO:0015948 methanogenesis
GO:0019251 anaerobic cobalamin biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6m2h, PDBe:6m2h, PDBj:6m2h
PDBsum6m2h
PubMed34163982
UniProtQ58380|CFBA_METJA Sirohydrochlorin cobaltochelatase (Gene Name=cbiX)

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