Structure of PDB 6lzn Chain A

Receptor sequence
>6lznA (length=316) Species: 1427 (Bacillus thermoproteolyticus) [Search protein sequence]
ITGTSTVGVGRGVLGDQKNINTTYSTYYYLQDNTRGNGIFTYDAKYRTTL
PGSLWADADNQFFASYDAPAVDAHYYAGVTYDYYKNVHNRLSYDGNNAAI
RSSVHYSQGYNNAFWNGSQMVYGDGDGQTFIPLSGGIDVVAHELTHAVTD
YTAGLIYQNESGAINEAISDIFGTLVEFYANKNPDWEIGEDVYTPGISGD
SLRSMSDPAKYGDPDHYSKRYTGTQDNGGVHINSGIINKAAYLISQGGTH
YGVSVVGIGRDKLGKIFYRALTQYLTPTSNFSQLRAAAVQSATDLYGSTS
QEVASVKQAFDAVGVK
3D structure
PDB6lzn Structural analysis of metal chelation of the metalloproteinase thermolysin by 1,10-phenanthroline.
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.24.27: thermolysin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H142 H146 E166 H142 H146 E166
BS02 CA A Y193 T194 I197 D200 Y193 T194 I197 D200
BS03 CA A D138 E177 D185 E187 E190 D138 E177 D185 E187 E190
BS04 CA A D57 D59 Q61 D57 D59 Q61
BS05 POL A T4 S5 T4 S5
BS06 ILE A N112 H142 E143 R203 N112 H142 E143 R203
BS07 LYS A N111 N112 F130 H231 N111 N112 F130 H231
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:6lzn, PDBe:6lzn, PDBj:6lzn
PDBsum6lzn
PubMed33310458
UniProtP00800|THER_BACTH Thermolysin (Gene Name=npr)

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