Structure of PDB 6ltd Chain A

Receptor sequence
>6ltdA (length=883) Species: 630397 (Streptomyces sp. Sp080513GE-23) [Search protein sequence]
AAELPPLVPEPGDAGQPFPLTPTQQALWVGRAYGYFEWERPELDLARYRR
AWERLVAHHPGLRTVVRPDGTQHVLERPGPVPITVEDLRQDPDAVRRLEE
SRLDPGTWPMFDLRVVLLSGRVRVQLGIDLQLMDASSLFLNLFSDLVTLY
DDPDAALASQKLAFRDFARWLEEDVRGGARWRADWAYWQERLDGLPPAPD
LPAARKFERCMVRCPAEEFALLRERALAHGLTETELLVGAFAEVLRGWSS
DPAFTLNVPVFQRFDVPGIEDVIGDYTNPILLEARPEGRTVAERIVALAA
RLRADTRHASVNGVEVLRELARRRGLAAAAMPVVVTSLLGLPSAARSITE
FGTEVHSITQTPQVSLDFQIRPEDGELRLVWDHRSGAFAPGVVEGAFEAF
LDLVGRMLADEPGHGVWEAPFADMRSRRDRAVWNETNDTAEPVPAVLLQE
RFFAQARRTPDAEAVVASGLRLTYDELARHAYRIGNTLRERGVRPGDLVG
VVMEKGWEQYAAVYGILAAGGAYLPIDAASPRGRVARLLESAGAGIVLTQ
SRLRDELDLPAGTTVLRADTDFETASTAPLTPVQGPDDPAYVIYTGEPKG
VVVAHRGVANLVRDVRRRFAVTPADRLLALSGLHFDASVYDVFGPLACGA
TVVVPPPFRRAEPDVWAELVRDERVTFWNSVPVLLELLVGEAESRDDRPL
ATLRLAVVSGDWIPLDLPGRARAQAPGLRVVGSGGPTETICWSLFHPIDA
VDPQWTSIPYGKPIANQRYYIVDRDLRPRPTWARGEMAVASPLGLALGYL
NDPERTAAKFVTLPGTGERAYLTGDFGRLLPDGGIEILGREDFQGQRIEL
GEIGVRAAADVVRRLLPELPLTANGKVDRLALA
3D structure
PDB6ltd Structural and Functional Analyses of the Tridomain-Nonribosomal Peptide Synthetase FmoA3 for 4-Methyloxazoline Ring Formation.
ChainA
Resolution4.1 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) T642 L662 T788 E789 R902 K982
Catalytic site (residue number reindexed from 1) T595 L611 T737 E738 R847 K876
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP A G761 D762 G786 P787 T788 D876 I888 R891 G710 D711 G735 P736 T737 D825 I837 R840
BS02 EW6 A D687 G786 P787 T788 D636 G735 P736 T737
Gene Ontology
Molecular Function
GO:0000036 acyl carrier activity
GO:0000166 nucleotide binding
GO:0003824 catalytic activity
GO:0031177 phosphopantetheine binding
Biological Process
GO:0006633 fatty acid biosynthetic process
GO:0008610 lipid biosynthetic process
GO:0017000 antibiotic biosynthetic process
GO:0043041 amino acid activation for nonribosomal peptide biosynthetic process
GO:0044550 secondary metabolite biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ltd, PDBe:6ltd, PDBj:6ltd
PDBsum6ltd
PubMed33783097
UniProtA0A077JG85

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