Structure of PDB 6lr8 Chain A

Receptor sequence
>6lr8A (length=518) Species: 3755 (Prunus dulcis) [Search protein sequence]
HHHHHHLANTSAHDFSYLKFVYNATDTSLEGSYDYIVIGGGTSGCPLAAT
LSEKYKVLLLERGTIATEYPNTLTADGFAYNLQQQDDGKTPVERFVSEDG
IDNVRARILGGTTIINAGVYARANISFYSQTGIEWDLDLVNKTYEWVEDA
IVVKPNNQSWQSVIGEGFLEAGILPDNGFSLDHEAGTRLTGSTFDNNGTR
HAADELLNKGDPNNLLVAVQASVEKILFSSNLSAIGVIYTDSDGNSHQAF
VRGNGEVIVSAGTIGTPQLLLLSGVGPESYLSSLNITVVQPNPYVGQFVY
DNPRNFINILPPNPIEASVVTVLGIRSDYYQVSASSLPFSTPPFSLFPTT
SYPLPNSTFAHIVSQVPGPLSHGSVTLNSSSDVRIAPNIKFNYYSNSTDL
ANCVSGMKKLGDLLRTKALEPYKARDVLGIDGFNYLGVPLPDDASFETFC
LDNVASYWHYHGGSLVGKVLDDSFRVMGIKALRVVDASTFPYEPNSHPQG
FYLMLGRYVGLQILQERS
3D structure
PDB6lr8 Structure-Guided Tuning of a Hydroxynitrile Lyase to Accept Rigid Pharmaco Aldehydes.
ChainA
Resolution1.595 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.1.2.10: (R)-mandelonitrile lyase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD A G33 G35 T36 E55 R56 A100 G105 T106 N110 A111 V113 V217 A258 W459 H460 A488 H498 P499 Q500 G39 G41 T42 E61 R62 A106 G111 T112 N116 A117 V119 V223 A261 W458 H459 A487 H497 P498 Q499
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
GO:0016829 lyase activity
GO:0046593 mandelonitrile lyase activity
GO:0050660 flavin adenine dinucleotide binding

View graph for
Molecular Function
External links
PDB RCSB:6lr8, PDBe:6lr8, PDBj:6lr8
PDBsum6lr8
PubMed
UniProtO24243|MDL1_PRUDU (R)-mandelonitrile lyase 1 (Gene Name=MDL1)

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