Structure of PDB 6lpg Chain A

Receptor sequence
>6lpgA (length=249) Species: 9606 (Homo sapiens) [Search protein sequence]
GGVPFFVNRGGLPVDEATWERMWKHVAKIHPDGEKVAQRIRGATDLPKIP
IPSVPTFQPSTPVPERLEAVQRYIRELQYNHTGTQFFEIKKSRPLTGLMD
LAKEMTKEALPIKCLEAVILGIYLTNSMPTLERFPISFKTYFSGNYFRHI
VLGVNFAGRYGALGMSRREDLMYKPPAFRTLSELVLDFEAAYGRCWHVLK
KVKLGQSVSHDPHSVEQIEWKHSVLDVERLGRDDFRKELERHARDMRLK
3D structure
PDB6lpg The crystal structure of the tetrameric human vasohibin-1-SVBP complex reveals a variable arm region within the structural core.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.17.17: tubulinyl-Tyr carboxypeptidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A L67 P68 V69 W74 V81 I84 H85 I95 R96 G97 A98 I104 P105 L132 Q133 Y134 H136 T137 F141 E163 A164 L165 P166 R222 L12 P13 V14 W19 V26 I29 H30 I40 R41 G42 A43 I49 P50 L77 Q78 Y79 H81 T82 F86 E108 A109 L110 P111 R167
Gene Ontology
Biological Process
GO:0045765 regulation of angiogenesis
Cellular Component
GO:0005737 cytoplasm

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Biological Process
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Cellular Component
External links
PDB RCSB:6lpg, PDBe:6lpg, PDBj:6lpg
PDBsum6lpg
PubMed33021501
UniProtQ7L8A9|VASH1_HUMAN Tubulinyl-Tyr carboxypeptidase 1 (Gene Name=VASH1)

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