Structure of PDB 6lkx Chain A

Receptor sequence
>6lkxA (length=441) Species: 28344 (Porcine reproductive and respiratory syndrome virus) [Search protein sequence]
KSRMCGYCGAPAPYATACGLDVCVYHTHFHQHCPVIIWCGHPAGSGSCSE
CEPPLGKGTSPLDEVLEQVPYKPPRTVIMHVEQGLTPLDPGRYQTRRGLV
SVRRGIRGNEVDLPDGDYASTALLPTCKEINMVAVASNVLRSRFIIGPPG
AGKTHWLLQQVQDGDVIYTPTHQTMLDMIRALGTCRFNVPAGTTLQFPAP
SRTGPWVRILAGGWCPGKNSFLDEAAYCNHLDVLRLLSKTTLTCLGDFKQ
LHPVGFDSHCYVFDIMPQTQLKTIWRFGQNICDAIQPDYRDKLMSMVNTT
RVTHVEKPVRYGQVLTPYHRDREDGAITIDSSQGATFDVVTLHLPTKDSL
NRQRALVAITRARHAIFVYDPHRQLQSMFDLPAKGTPVNLAVHRDEQLIV
LDRNNREITVAQALGNGDKFRATDKRVVDSLRAICADLELE
3D structure
PDB6lkx Structural Characterization of the Helicase nsp10 Encoded by Porcine Reproductive and Respiratory Syndrome Virus.
ChainA
Resolution2.998 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N140 M177 V394 Q399 L400
Catalytic site (residue number reindexed from 1) N138 M175 V392 Q397 L398
Enzyme Commision number 3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C10 C25 H28 C8 C23 H26
BS02 ZN A C41 H43 C50 C53 C39 H41 C48 C51
BS03 ZN A C20 H32 H34 C35 C18 H30 H32 C33
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:6lkx, PDBe:6lkx, PDBj:6lkx
PDBsum6lkx
PubMed32461315
UniProtD2CSC7

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