Structure of PDB 6ljr Chain A

Receptor sequence
>6ljrA (length=140) Species: 9606 (Homo sapiens) [Search protein sequence]
MSFLTVPYKLPVSLSVGSCVIIKGTLIDSSINEPQLQVDFYTEMNEDSEI
AFHLNVRLGRRVVMNSREFGIWMLEENLHYVPFEDGKPFDLRIYVCLNEY
EVKVNGEYIYAFVHRIPPSYVKMIQVWRDVSLDSVLVNNG
3D structure
PDB6ljr Human galectin-16 has a pseudo ligand binding site and plays a role in regulating c-Rel-mediated lymphocyte activity.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BGC A R64 E78 R61 E75
BS02 GAL A H56 N68 W75 E78 H53 N65 W72 E75
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding
GO:0030395 lactose binding
Biological Process
GO:0006915 apoptotic process
GO:0070234 positive regulation of T cell apoptotic process
Cellular Component
GO:0005575 cellular_component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ljr, PDBe:6ljr, PDBj:6ljr
PDBsum6ljr
PubMed33011338
UniProtA8MUM7|LEG16_HUMAN Galectin-16 (Gene Name=LGALS16)

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