Structure of PDB 6lcb Chain A

Receptor sequence
>6lcbA (length=82) Species: 9606 (Homo sapiens) [Search protein sequence]
NIVTVTLNMERHHFLGISIVGIYIGSIMKGGAVAADGRIEPGDMLLQVND
VNFENMSNDDAVRVLREIVSQTGPISLTVAKA
3D structure
PDB6lcb Crystal structure of human Dishevelled1 PDZ domain with its inhibitor NPL3009
ChainA
Resolution1.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 E83 A F261 L262 G263 I264 L321 R322 V325 F14 L15 G16 I17 L65 R66 V69
Gene Ontology
Biological Process
GO:0016055 Wnt signaling pathway

View graph for
Biological Process
External links
PDB RCSB:6lcb, PDBe:6lcb, PDBj:6lcb
PDBsum6lcb
PubMed
UniProtO14640|DVL1_HUMAN Segment polarity protein dishevelled homolog DVL-1 (Gene Name=DVL1)

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