Structure of PDB 6l7v Chain A

Receptor sequence
>6l7vA (length=180) Species: 353153 (Trypanosoma cruzi strain CL Brener) [Search protein sequence]
DAEQRAVAKALFDAVNKHLSNPFIEVEMRLGQFKANFTACVSTEDYERIK
TYLMTEMENSSMTRSVTHDVWRHTYATDENGNPTRCVSIVRKKRLFVKNI
VVPLGAYNLRFAVSTETPTRLKDRLSITDGMFRYDMTQVTEKGVLMHEVE
IEGVFSSKQLTESWLEELLRRAMRLATLRT
3D structure
PDB6l7v Crystal structures of the RNA triphosphatase fromTrypanosoma cruziprovide insights into how it recognizes the 5'-end of the RNA substrate.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.74: mRNA 5'-phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A E42 E44 E210 E25 E27 E150
BS02 3PO A E42 R46 R118 K138 E162 K182 R184 E25 R29 R72 K92 E116 K122 R124
Gene Ontology
Molecular Function
GO:0004651 polynucleotide 5'-phosphatase activity

View graph for
Molecular Function
External links
PDB RCSB:6l7v, PDBe:6l7v, PDBj:6l7v
PDBsum6l7v
PubMed32381506
UniProtQ4E2I1

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