Structure of PDB 6l5o Chain A

Receptor sequence
>6l5oA (length=372) Species: 9606 (Homo sapiens) [Search protein sequence]
SFSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGK
TFSFAIPLIEKLHGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDITKK
LSVACFYGGTPYGGQFERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHV
VLDEVDQMLDMGFADQVEEILSVAYKKDSEDNPQTLLFSATCPHWVFNVA
KKYMKSTYEQVDLIKTAITVEHLAIKCHWTQRAAVIGDVIRVYSGHQGRT
IIFCETKKEAQELSQNSAIKQDAQSLHGDIPQKQREITLKGFRNGSFGVL
VATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICFY
QHKEEYQLVQVEQKAGIKFKRI
3D structure
PDB6l5o Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A V206 F210 Q213 G233 G235 K236 T237 V20 F24 Q27 G47 G49 K50 T51
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003724 RNA helicase activity
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:6l5o, PDBe:6l5o, PDBj:6l5o
PDBsum6l5o
PubMed32714761
UniProtQ9NR30|DDX21_HUMAN Nucleolar RNA helicase 2 (Gene Name=DDX21)

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