Structure of PDB 6l5m Chain A

Receptor sequence
>6l5mA (length=366) Species: 9606 (Homo sapiens) [Search protein sequence]
FSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKT
FSFAIPLIEKLHGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDITKKL
SVACFYGGTPYGGQFERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVV
LDEVDQMLDMGFADQVEEILSVAYKKDSEDNPQTLLFSATCPHWVFNVAK
KYMKSTYEQVDLTVEHLAIKCHWTQRAAVIGDVIRVYSGHQGRTIIFCET
KKEAQELSQNSAIKQDAQSLHGDIPQKQREITLKGFRNGSFGVLVATNVA
ARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICFYQHKEEY
QLVQVEQKAGIKFKRI
3D structure
PDB6l5m Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation.
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP A V206 F210 Q213 G233 G235 K236 T237 V19 F23 Q26 G46 G48 K49 T50
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003724 RNA helicase activity
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:6l5m, PDBe:6l5m, PDBj:6l5m
PDBsum6l5m
PubMed32714761
UniProtQ9NR30|DDX21_HUMAN Nucleolar RNA helicase 2 (Gene Name=DDX21)

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