Structure of PDB 6l3e Chain A

Receptor sequence

>6l3eA (length=365) Species: 28901 (Salmonella enterica)

EGKLVIWINGDKGYNGLAEVGKKFEQDTGIKVTVEHPDKLEEKFPQVAAT
GDGPDIIFWAHDRFGGYAQSGLLAEVTPDKAFQDKLYPFTWDAVRYNGKL
IAYPIAVEALSLIYNKDLVPNPPKTWEEIPALDKELKVKGKSAIMFNLQE
PYFTWPLIAADGGYAFKFENKYDVKDVGVDNAGAKAGLTFLIDMIKNKNM
SADTDYSIAEAAFNKGETAMTINGPWAWSNIDKSKVNYGVTLLPTFKGKP
SKPFVGVLSAGINAASPNKELAKEFLENYLLTDQGLEAVNKDKPLGAVAL
KSFQEQLAKDPRIAATMDNAQKGEIMPNIPQMSAFWYAVRTAVINAASGR
QTVDAALKDAQSRIT

3D structure

• PDB: 6l3e The crystal structure of Salmonella enterica sugar-binding protein MalE
• Chain: A
• Resolution: 1.6 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	GLC	A	D14 K15 E111 Y155 W230	D11 K12 E108 Y152 W226
BS02	GLC	A	W62 D65 E153 P154 Y155 W340	W59 D62 E150 P151 Y152 W336
BS03	GLC	A	E44 R66 E153 W340 Y341 R344	E41 R63 E150 W336 Y337 R340
BS04	GLC	A	E44 E45 R344	E41 E42 R340
BS05	2ME	A	R344 T345	R340 T341
BS06	2ME	A	Y90 M321	Y87 M317
BS07	MG	A	K42 E44	K39 E41

Gene Ontology

Molecular Function

• GO:0015144 carbohydrate transmembrane transporter activity
• GO:1901982 maltose binding

Biological Process

• GO:0008643 carbohydrate transport
• GO:0015768 maltose transport
• GO:0034219 carbohydrate transmembrane transport
• GO:0042956 maltodextrin transmembrane transport
• GO:0055085 transmembrane transport

Cellular Component

• GO:0030288 outer membrane-bounded periplasmic space
• GO:0042597 periplasmic space
• GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

External links

• PDB: RCSB:6l3e, PDBe:6l3e, PDBj:6l3e
• PDBsum: 6l3e
• UniProt: P19576|MALE_SALTY Maltose/maltodextrin-binding periplasmic protein (Gene Name=malE)