Structure of PDB 6l1w Chain A

Receptor sequence

>6l1wA (length=215) Species: 10090 (Mus musculus) [Search protein sequence]

PEVFCFITKILCAHGGRMTLEELLGEISLPEAQLYELLKAAGPDRFVLLE
TRSVVATTRARVCRRKYCQRPCDSLHLCKLNLLGRCHYAQSQRNLCKYSH
DVLSEQNFQVLKNHELSGLNQEELAVLLVQSDPFFMPEICKSYKGEGRKQ
ICGQPQPCERLHICEHFTRGNCSYLNCLRSHNLMDRKVLAIMREHGLSSD
VVQNIQDICNNKHTR

3D structure

PDB

6l1w Molecular Mechanism of RNA Recognition by Zinc-Finger Antiviral Protein.

Chain

Resolution

2.194 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	rna	A	C88 K89 L90 H97 Y98 L105 C106 K107 Y108 F144 E148 I149 C150 K151 R170	C78 K79 L80 H87 Y88 L95 C96 K97 Y98 F134 E138 I139 C140 K141 R160
BS02	ZN	A	C88 C96 C106 H110	C78 C86 C96 H100
BS03	ZN	A	C73 C78 C82 H86	C63 C68 C72 H76
BS04	ZN	A	C150 C162 C168 H172	C140 C152 C158 H162
BS05	ZN	A	C174 C182 C187 H191	C164 C172 C177 H181

Gene Ontology

	Molecular Function
GO:0046872	metal ion binding

View graph for
Molecular Function

External links

PDB	RCSB:6l1w, PDBe:6l1w, PDBj:6l1w
PDBsum	6l1w
PubMed	31914396
UniProt	Q3UPF5\|ZCCHV_MOUSE Zinc finger CCCH-type antiviral protein 1 (Gene Name=Zc3hav1)

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