Structure of PDB 6kzh Chain A

Receptor sequence
>6kzhA (length=230) Species: 9606 (Homo sapiens) [Search protein sequence]
QGEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYK
NVVGGRRSAWRVISSIEQKTTSDKKLQLIKDYREKVESELRSICTTVLEL
LDKYLIANATNPESKVFYLKMKGDYFRYLAEVACGDDRKQTIDNSQGAYQ
EAFDISKKEMQPTHPIRLGLALNFSVFYYEILNNPELACTLAKTAFDEAI
AELDTLNEDSYKDSTLIMQLLRDNLTLWTS
3D structure
PDB6kzh 14-3-3 protein in Complex with CIC S173 phosphorylated peptide
ChainA
Resolution2.645 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A K49 R56 R127 Y128 L172 N173 E180 L220 D223 N224 W228 K50 R57 R127 Y128 L172 N173 E180 L220 D223 N224 W228
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0019904 protein domain specific binding
GO:0042802 identical protein binding
GO:0044325 transmembrane transporter binding
GO:0071889 14-3-3 protein binding
Biological Process
GO:0006605 protein targeting
GO:0007165 signal transduction
GO:0007264 small GTPase-mediated signal transduction
GO:0008104 protein localization
GO:0021762 substantia nigra development
GO:0034766 negative regulation of monoatomic ion transmembrane transport
GO:0045892 negative regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005925 focal adhesion
GO:0016020 membrane
GO:0032991 protein-containing complex
GO:0045202 synapse
GO:0070062 extracellular exosome

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Biological Process
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Cellular Component
External links
PDB RCSB:6kzh, PDBe:6kzh, PDBj:6kzh
PDBsum6kzh
PubMed
UniProtP27348|1433T_HUMAN 14-3-3 protein theta (Gene Name=YWHAQ)

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