Structure of PDB 6kx7 Chain A

Receptor sequence
>6kx7A (length=476) Species: 10090 (Mus musculus) [Search protein sequence]
VNAVHWFRKGLRLHDNPALKECIQGADTIRCVYILDPWFAGSSNVGINRW
RFLLQCLEDLDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDS
EPFGKERDAAIKKLATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKR
FQTLVSKMEPLEPADTITSDVIGKCMTPLSDDHDEKYGVPSLEELGFDTD
GLSSAVWPGGETEALTRLERHLERKNANSLLASPTGLSPYLRFGCLSCRL
FYFKLTDLYKKVKPPLSLYGQLLWREFFYTAATNNPRFDKMEGNPICVQI
PWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRG
DLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGF
GRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPK
PMVNHAEASRLNIERMKQIYQQLSRY
3D structure
PDB6kx7 Isoform-selective regulation of mammalian cryptochromes.
ChainA
Resolution2.1 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Q289 W292 W320 H355 W374 W397
Catalytic site (residue number reindexed from 1) Q271 W274 W302 H337 W356 W379
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 DYX A Q289 W292 R293 H355 R358 H359 F381 I392 S396 W397 W399 L400 Q271 W274 R275 H337 R340 H341 F363 I374 S378 W379 W381 L382
External links
PDB RCSB:6kx7, PDBe:6kx7, PDBj:6kx7
PDBsum6kx7
PubMed32231341
UniProtP97784|CRY1_MOUSE Cryptochrome-1 (Gene Name=Cry1)

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