Structure of PDB 6kvq Chain A

Receptor sequence

>6kvqA (length=308) Species: 1280 (Staphylococcus aureus) [Search protein sequence]

GHMATLKVIGVGGGGNNAVNRMIDHGMNNVEFIAINTDGQALNLSKAESK
IQIGEKLTRGLGAGANPEIGKKAAEESREQIEDAIQGADMVFVTSGMGGG
TGTGAAPVVAKIAKEMGALTVGVVTRPFSFEGRKRQTQAAAGVEAMKAAV
DTLIVIPNDRLLDIVDKSTPMMEAFKEADNVLRQGVQGISDLIAVSGEVN
LDFADVKTIMSNQGSALMGIGVSSGENRAVEAAKKAISSPLLETSIVGAQ
GVLMNITGGESLSLFEAQEAADIVQDAADEDVNMIFGTVINPELQDEIVV
TVIATGFD

3D structure

PDB

6kvq Structure-Guided Design of a Fluorescent Probe for the Visualization of FtsZ in Clinically Important Gram-Positive and Gram-Negative Bacterial Pathogens.

Chain

Resolution

1.6 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	GDP	A	G20 G21 G22 N25 R29 G104 G107 T109 G110 P135 E139 R143 N166 F183	G12 G13 G14 N17 R21 G96 G99 T101 G102 P127 E131 R135 N158 F175
BS02	CA	A	L200 V203 N208 L209	L192 V195 N200 L201
BS03	DVX	A	G193 G196 I197 D199 L200 V203 G205 L209 M218 M226 I228 V230 L261 N263 V297 V307 T309 V310 I311	G185 G188 I189 D191 L192 V195 G197 L201 M210 M218 I220 V222 L253 N255 V289 V299 T301 V302 I303	MOAD: Kd=0.88uM

Gene Ontology

	Molecular Function
GO:0003924	GTPase activity
GO:0005525	GTP binding

View graph for
Molecular Function

External links

PDB	RCSB:6kvq, PDBe:6kvq, PDBj:6kvq
PDBsum	6kvq
PubMed	31882782
UniProt	Q6GHP9\|FTSZ_STAAR Cell division protein FtsZ (Gene Name=ftsZ)

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