Structure of PDB 6ko5 Chain A

Receptor sequence
>6ko5A (length=398) Species: 562,9606 [Search protein sequence]
DLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPPKLEDK
SPDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAY
IQKYLPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLS
SMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYAKVLT
ITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVG
VEHEQGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYS
LIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGR
YLFSKSFEPSQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLG
3D structure
PDB6ko5 Structure of an antagonist-bound ghrelin receptor reveals possible ghrelin recognition mode.
ChainA
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 8QX A D99 R102 S123 E124 I178 L181 R283 F286 F309 F312 D166 R169 S190 E191 I245 L248 R350 F353 F368 F371
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0005506 iron ion binding
GO:0009055 electron transfer activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0022900 electron transport chain
Cellular Component
GO:0016020 membrane
GO:0042597 periplasmic space

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Cellular Component
External links
PDB RCSB:6ko5, PDBe:6ko5, PDBj:6ko5
PDBsum6ko5
PubMed32814772
UniProtP0ABE7|C562_ECOLX Soluble cytochrome b562 (Gene Name=cybC);
Q92847|GHSR_HUMAN Growth hormone secretagogue receptor type 1 (Gene Name=GHSR)

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