Structure of PDB 6knc Chain A

Receptor sequence
>6kncA (length=450) Species: 69014 (Thermococcus kodakarensis KOD1) [Search protein sequence]
YSTYSDLVIAPKEGFHYRAKEIPDEWELAFDVKNVKFEVPKVKNAQSKEG
EVIIQAYSSYFKSRLKKMRRIFRENPEIGTIVDIAKLSYVREDDVTIIGL
VNEKRETRKGYLFEIEDATGRIKVFIGSDKEGANEAYSTIMPDSVVAFRG
TPGKGIFFANRVFLPDVPKFKRSKPPLEEKVYAILLSDIHVGSNKFCEEA
FIKFLEWLNGEVNSRTEEELVSRIKYIIIGGDVVDGVGIYPGQYNELAIP
DIFDQYEALANLLKQVPDHITMFIGPGNHDAARTALPQPGFYEEYAKPLY
KLKNAVIISNPAVIRLHGRDFLVAHGRGIEDVVDFVPNRSHHRPAEAMVE
LLKLRHIAPTFGNKVPIAPDPEDTLVIESVPDLFQAGHVHVMQYKTYNGV
FVINTGTWQAQTEFQKMVNIIPTPARVPIIDVETARLRAVVRFDQFCEGV
3D structure
PDB6knc Two conformations of DNA polymerase D-PCNA-DNA, an archaeal replisome complex, revealed by cryo-electron microscopy.
ChainA
Resolution9.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
3.1.11.1: exodeoxyribonuclease I.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 FE A D473 H475 H675 D188 H190 H390
BS02 ZN A D473 D517 H610 H673 D188 D232 H325 H388
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0008408 3'-5' exonuclease activity
Biological Process
GO:0006260 DNA replication

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:6knc, PDBe:6knc, PDBj:6knc
PDBsum6knc
PubMed33115459
UniProtQ5JET1

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