Structure of PDB 6km9 Chain A

Receptor sequence
>6km9A (length=844) Species: 216895 (Vibrio vulnificus CMCP6) [Search protein sequence]
DAKQVKVLQLINAYRFRGHEAAELDPLGLWQRPTVAELDPAFHNLTEDDF
EETFNVGSFAVGQETMPLKDIYTALKKTYCGSIGAEYMHMTDTEQKRWIQ
QRLESVVGQPSFDKDEKRTFLAELTAAEGLERYLGAKFPGAKRFSLEGGD
AMIPMMKELIRHAGRSGMREVVIGMAHRGRLNMLVNVLGKKPQDLFDEFA
GKHGESWGTGDVKYHQGFSADFATPGGDVHLALAFNPSHLEIVNPVVMGS
VRARQDRLGDDDGSKVLPITIHGDSAIAGQGVVAETFNMSQARGFCVGGT
VRVVVNNQVGFTTSNPRDTRSTMYCTDIAKMVQAPIFHVNADDPEAVAFV
TRIALDYRNEFKRDVVIDLVCYRRHGHNEADEPNATQPLMYQKIKKHPTP
RKLYADVLIDRNECDIETATQMVNEYRDALDHGEVVVKEWRPMALWSPYL
GHEWDTPWSNTYDKQRLVELGKRLCQYPESHTLHSRVSKLYNDRTAMTNG
EKELDWGMAETLAYATLVDDGKRIRISGQDSGRGTFFHRHAVLHNQNDAS
TYVPLANIHDKQGPFEVFDSVLSEEAVLAFEYGYATAEPSGLTLWEAQFG
DFANGAQVVIDQFISSGEQKWARLCGLTMLLPHGYEGQGPEHSSARLERY
LQLCAEQNMQVVVPSTPAQVYHMIRRQVVRPMRRPLIVMSPKSLLRHPLC
TSSLDDLANGTFMPAIPEIDELDPAKVKRVVFCSGKVYFDLLEQRRNNEQ
DDVAIVRIEQLYPFPMDDVKAAIAPYVNVEDFVWCQEEPQNQGAWYCSQH
NFRAAIPAGTELKYAGRPASASPAVGYMSVHLKQQKALIDDALN
3D structure
PDB6km9 Understanding the molecular properties of the E1 subunit (SucA) of alpha-ketoglutarate dehydrogenase complex from Vibrio vulnificus for the enantioselective ligation of acetaldehydes into (R)-acetoin.
ChainA
Resolution2.724 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.2.4.2: oxoglutarate dehydrogenase (succinyl-transferring).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D360 N393 V395 D274 N307 V309
BS02 TPP A H263 R264 S324 H325 L326 G359 D360 S361 A362 Q366 N393 V395 G396 H463 H177 R178 S238 H239 L240 G273 D274 S275 A276 Q280 N307 V309 G310 H377
BS03 TPP A Q619 L662 E664 Q688 F692 Q529 L572 E574 Q598 F602
Gene Ontology
Molecular Function
GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity
GO:0016491 oxidoreductase activity
GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GO:0030976 thiamine pyrophosphate binding
GO:0046872 metal ion binding
Biological Process
GO:0006099 tricarboxylic acid cycle
Cellular Component
GO:0005829 cytosol
GO:0045252 oxoglutarate dehydrogenase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6km9, PDBe:6km9, PDBj:6km9
PDBsum6km9
PubMed
UniProtA0A3Q0L1E1

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